Publications

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2010
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2018
243. Marengo A., Forciniti S., Dando I., Elisa DallaPozza E., Stella B., Tsapis N. Yagoubi N., Fanelli G., Fattal E., Heeschen C., Palmieri M., Arpicco S. Pancreatic cancer stem cell proliferation is strongly inhibited by diethyldithiocarbamate‑copper complex loaded into hyaluronic acid decorated liposomes. Biochimica et Biophysica Acta (BBA) – General Subjects https://doi.org/10.1016/j.bbagen.2018.09.018
242. Alshaer W., Hillaireau H., Fattal E., Aptamer-guided nanomedicines for anticancer drug delivery. Advanced drug delivery reviews –  https://doi.org/10.1016/j.addr.2018.09.011
241. Giacalone G., Tsapis N., Mousnier L., Chacun H., Fattal E. PLA-PEG nanoparticles improve the anti-inflammatory effect of Rosiglitazone on macrophages by enhancing drug uptake compared to free Rosiglitazone. Materials , 11(10), 1845, 2018 – https://doi.org/10.3390/ma11071167
240. Sauvage F, Fattal E, Al-Shaer W, Denis S, Brotin E, Denoyelle C, Blanc-Fournier C, Toussaint B, Messaoudi S, Alami M, Barratt G, Vergnaud-Gauduchon J. Antitumor activity of nanoliposomes encapsulating the novobiocin analogue 6BrCaQ in a triple-negative breast cancer model in mice. Cancer Letters -432, 103-111, 2018 https://doi.org/10.1016/j.canlet.2018.06.001
239. Deriu M.A., Tsapis N., Noiray M., Grasso G., El Brahmi N., Mignani S, Majoral J.P., Fattal E. Danani A. Elucidating the Role of Surface Chemistry on Cationic Phosphorus Dendrimer-siRNA Complexation. Nanoscale – 10, 10952-10962, 2018 – https://doi.org/10.1039/C8NR01928B
238. Alshaer, W., Hillaireau, H., Vergnaud, J., Mura S., Deloménie C., Sauvage F., Ismail S., Fattal, E., Aptamer-guided siRNA-loaded nanomedicines for systemic gene silencing in CD-44 expressing murine triple-negative breast cancer model. Journal of Controlled Release – 271, 198-106, 2018 https://doi.org/10.1016/j.jconrel.2017.12.022
237. Tortolano L., Saunier J., Hammami S., Manerlax K., Matmati H., Do B., Jubeli E., Fattal E., Yagoubi N. Restructuration kinetics of amphiphilic intraocular lenses during aging. Colloids and Surface B, 161, (1), 20-432, 2018 – https://doi.org/10.1016/j.colsurfb.2017.11.007
236. Leng D., Thanki K., Fattal E., Foged C., Yang M. Engineering of budesonide-loaded lipid-polymer hybrid nanoparticles using a quality-by-design approach. International Journal of Pharmaceutics 548)(2),  740-746, 2018 – https://doi.org/10.1016/j.ijpharm.2017.08.094
235. N’Guessan A., Fattal E., Chapron D., Gueutin C., Koffi A., Tsapis N., Dexamethasone palmitate large porous particles: a controlled release formulation for lung delivery of corticosteroids. European Journal of Pharmaceutical Sciences, 113, 185-192, 2018 – https://doi.org/10.1016/j.ejps.2017.09.013
2017
234. Teixeira HF, Bruxel F, Fraga M, Schuh RS, Zorzi GK, Matte U, Fattal E. Cationic nanoemulsions as nucleic acids delivery systems. International Journal of Pharmaceutics 534, (1–2), 356-367, 2017 – https://doi.org/10.1016/j.ijpharm.2017.10.030
233. Boissenot T., Bordat A., Larrat B., Varna M., Chacun H., Paci A., Poinsignon V., Fattal E., Tsapis N., Ultrasound-induced mild hyperthermia improves the anticancer efficacy of both Taxol® and paclitaxel-loaded nanocapsules. Journal of Controlled Release, 264, 219-227, 2017 – https://doi.org/10.1016/j.jconrel.2017.08.041/
232. Deschamps F, Moine L, Isoardo T, Tselikas L, Paci A, Mir LM, Huang N, Fattal E, de Baère T. Parameters for stable water-in-oil lipiodol emulsion for liver trans-arterial chemo-embolization. CardioVascular and Interventional Radiology 40, (12), 1927–1932, 2017 – https://doi.org/10.1007/s00270-017-1763-5
231. Bohr A, Tsapis N, Andreana I, Chamarat A, Foged C, Delomenie C, Noiray M, El Brahmi N, Majoral JP, Mignani S, Fattal E. Anti-inflammatory effect of anti-TNF-α siRNA cationic phosphorous dendrimers nanocomplexes administered intranasally in a murine acute lung injury model. Biomacromolecules, 18 (8), 2379–2388, 2017 – https://doi.org/10.1021/acs.biomac.7b00572
230. Cosco D, Tsapis N, Nascimento TL, Fresta M, Chapron D, Taverna M, Arpicco S, Fattal E. Polysaccharide-coated liposomes by post-insertion of a hyaluronan-lipid conjugate. Colloids and Surfaces B: Biointerfaces 158C, 119-126, 2017 – https://doi.org/10.1016/j.colsurfb.2017.06.029
229. Gokce EH, Tuncay Tanrıverdi S, Eroglu I, Tsapis N, Gokce G, Tekmen I, Fattal E, Ozer O. Wound healing effects of collagen-laminin dermal matrix impregnated with resveratrol loaded hyaluronic acid-DPPC microparticles in diabetic rats. European journal of pharmaceutics and biopharmaceutics, 119, 17-27, 2017 – https://doi.org/10.1016/j.ejpb.2017.04.027
228. Manconi M., Manca M. L., Valenti D., Escribano E., Hillaireau H., Fadda A. M., Fattal E., Chitosan and hyaluronan coated liposomes for pulmonary administration of curcumin. International Journal of Pharmaceutics 1(15), 203-210, 2017 – https://doi.org/10.1016/j.ijpharm.2017.04.044.
227. Sauvage F, Messaoudi S, Fattal E, Barratt G, Vergnaud-Gauduchon J. Heat shock proteins and cancer: How can nanomedicine be harnessed? Journal of Controlled Release, 248:133-143, 2017 – https://doi.org/10.1016/j.jconrel.2017.01.013.
226. Martens TF, Peynshaert K, Nascimento TL, Fattal E, Karlstetter M, Langmann T, Picaud S, Demeester J, De Smedt SC, Remaut K, Braeckmans K. Effect of hyaluronic acid-binding to lipoplexes on intravitreal drug delivery for retinal gene therapy. European Journal of Pharmaceutical Sciences 103:27-35, 2017 – https://doi.org/10.1016/j.ejps.2017.02.027
225. Grivès S, Phan G, Bouvier-Capely C, Suhard D, Rebière F, Agarande M, Fattal E. Compared in vivo efficiency of nanoemulsions unloaded and loaded with calixarene and soapy water in the treatment of superficial wounds contaminated by uranium. Chemico-Biological Interactions, 267:33–39, 2017 – https://doi.org/10.1016/j.cbi.2016.11.030
2016
224. Ruge C., Hillaireau H., Grabowski N., Beck-Broichsitter M., Canadas O., Tsapis N., Casals C., Nicolas J., Fattal, E. Pulmonary surfactant protein a – mediated enrichment of surface-decorated polymeric nanoparticles in alveolar macrophages. Molecular Pharmaceutics, 13(12):4168-4178, 2016 – https://doi.org/10.1021/acs.molpharmaceut.6b00773
223. Boissenot T, Fattal E, Bordat A, Houvenagel S, Valette J, Chacun H, Gueutin C, Tsapis N. Paclitaxel-Loaded PEGylated Nanocapsules of Perfluorooctyl Bromide as Theranostic Agents. European Journal of Pharmaceutics and Biopharmaceutics. 108:136-144, 2016 – https://doi.org/10.1016/j.ejpb.2016.08.017
222. Leite Nascimento T., Hillaireau H., Vergnaud J.,  Rivano M., Deloménie C., Courilleau D., Arpicco S., Soo Suk J., Hanes J., Fattal E. Hyaluronic acid-conjugated lipoplexes for targeted delivery of siRNA in a murine metastatic lung cancer model. International Journal of Pharmaceutics. 514(1):103-111, 2016 – https://doi.org/10.1016/j.ijpharm.2016.06.125
221. Boissenot T., Bordat A., Fattal E., Tsapis N. Ultrasound-triggered drug delivery for cancer treatment using drug delivery systems: From theoretical considerations to practical applications. Journal of Controlled Release, 241, 10, 144–163, 2016 – https://doi.org/10.1016/j.jconrel.2016.09.026
220. Diou O, Brûlet A, Pehau-Arnaudet G, Morvan E, Berti R, Astafyeva K, Taulier N, Fattal E, Tsapis N. PEGylated nanocapsules of perfluorooctyl bromide: Mechanism of formation, influence of polymer concentration on morphology and mechanical properties. Colloids and Surfaces B: biointerfaces, 146:762-769, 2016 – https://doi.org/10.1016/j.colsurfb.2016.07.033
219. Leite Nascimento T., Hillaireau H., Vergnaud J., Fattal E. Lipid based nanosystems for CD44 targeting in cancer treatment: recent significant advances, ongoing challenges and unmet needs. Nanomedicine, 12(1):135-46, 2016 – https://doi.org/10.2217/nnm-2016-5000
218. Dosio F., Arpicco S., Stella B., Fattal E. Hyaluronic acid for anticancer drug and nucleic acid delivery Advanced Drug Delivery Reviews, 97, 204–236, 2016 – https://doi.org/10.1016/j.addr.2015.11.011
217. Ruge C., Bohr A., Beck-Broichsitter M., Nicolas V., Tsapis N., Fattal E. Disintegration of nano-embedded microparticles after deposition on mucus: a mechanistic study. Colloids and Surfaces B: biointerfaces, 139, 219–227, 2016 – https://doi.org/10.1016/j.colsurfb.2015.12.017
216. Santiago, L, Hillaireau, H., Grabowski, N., Mura, S., Nascimento, T., Dufort, S., Coll, J-L, Tsapis, N., Fattal, E., Compared in vivo toxicity in mice of lung delivered biodegradable and non-biodegradable nanoparticles Nanotoxicology, 10(3):292-302, 2016 – https://doi.org/10.3109/17435390.2015.1054908
215.  Grabowski, N., Hillaireau, H., Vergnaud, J., Nicolas V., Tsapis, N., Kerdine-Romer S., Fattal, E., Surface-modified biodegradable nanoparticles’ impact on cytotoxicity and inflammation response on a co-culture of lung epithelial cells and human-like macrophages. Journal of Biomedical Nanotechnology, 12, 135-146, 2016 – https://doi.org/10.1166/jbn.2016.2126
2015
214. Nascimento T L, Hillaireau H, Fattal E. Noiray M., Bourgaux C., Arpicco S., Pehau-Arnaudet G., Taverna M., Cosco D., Tsapis N., Fattal E. Supramolecular organization and siRNA binding of hyaluronic acid-coated lipoplexes for targeted delivery to CD44 receptor. Langmuir, 31(41):11186-11194, 2015 – https://doi.org/10.1021/acs.langmuir.5b01979
213. Pham D., Fattal E., Tsapis N., Pyrazinamide-loaded poly(lactide-co-glycolide) nanoparticles: Optimization by experimental design. Journal of Drug Delivery Science and Technology, 30, 384-390, 2015 – https://doi.org/10.1016/j.jddst.2015.07.006
212. Reynaud F., Tsapis N., Guterres S.S., Pohlmann A.R., Fattal E., Pectin beads loaded with chitosan-iron microspheres for specific colonic adsorption of ciprofloxacin. Journal of Drug Delivery Science and Technology, 30, 494-500, 2015 – https://doi.org/10.1016/j.jddst.2015.07.014
211. Fattal E, Tsapis N, Phan G., Novel drug delivery systems for actinides (uranium and plutonium) decontamination agents. Advanced Drug Delivery Reviews, 90, 40-54 2015 – https://doi.org/10.1016/j.addr.2015.06.009
210. Pham DD, Grégoire N, Couet W, Gueutin C, Fattal E, Tsapis N., Pulmonary delivery of pyrazinamide-loaded large porous particles. European Journal of Pharmaceutics and Biopharmaceutics, 94, 241-250, 2015 – https://doi.org/10.1016/j.ejpb.2015.05.021
209. Giacalone, G., Hillaireau, H., Fattal, E., Improving bioavailability and biodistribution of anti-HIV chemotherapy European Journal of Pharmaceutical Sciences. 75: 40-53, 2015 – https://doi.org/10.1016/j.ejps.2015.04.011
208. Novell, A., Al Sabbagh, C., Escoffre, J.M., Gaillard, C., Tsapis, N., Fattal, E., Bouakaz, A., Focused ultrasound influence on calcein-loaded thermosensitive stealth liposomes. Int J Hyperthermia. 31:349-358, 2015 – https://doi.org/10.3109/02656736.2014.1000393
207. Grivès, S., Phan, G., Morat, G., Suhard, D., Rebière, F., Fattal, E., Ex vivo uranium decontamination efficiency on wounded skin and in vitro skin toxicity of a calixarene-loaded nanoemulsion. Journal of Pharmaceutical Sciences. 104(6):2008-2017, 2015 – https://doi.org/10.1002/jps.24431
206. Eroğlu İ, Gökçe EH, Tsapis N, Tanrıverdi ST, Gökçe G, Fattal E, Özer Ö Evaluation of characteristics and in vitro antioxidant properties of RSV loaded hyaluronic acid-DPPC microparticles as a wound healing system. Colloids and Surface B Biointerfaces,126:50-7, 2015 – https://doi.org/10.1016/j.colsurfb.2014.12.006
205. Pham D, Fattal E, Tsapis N. Pulmonary drug delivery systems for tuberculosis treatment. International Journal of Pharmaceutics. 478(2):517-29, 2015 – https://doi.org/10.1016/j.ijpharm.2014.12.009
204. Cosco D, Paolino D, Angelis FD, Cilurzo F, Celia C, Marzio LD, Russo D, Tsapis N, Fattal E, Fresta M. Aqueous-core PEG-coated PLA nanocapsules for an efficient entrapment of water soluble anticancer drugs and a smart therapeutic response. European Journal of Pharmaceutics and Biopharmaceutics 89:30-9, 2015 – https://doi.org/10.1016/j.ejpb.2014.11.012
203. Grabowski N, Hillaireau H, Vergnaud J, Tsapis N1, Pallardy M, Kerdine-Römer S, Fattal E. Surface coating mediates the toxicity of polymeric nanoparticles towards human-like macrophages. International Journal of Pharmaceutics. 482(1-2):75-83, 2015 – https://doi.org/10.1016/j.ijpharm.2014.11.042
202. Cosco, D., Fattal, E., Fresta, M., Tsapis N., Perfluorocarbon-loaded micro and nanosystems for medical imaging: a state of the art. Journal of Fluorine Chemistry. 171:18-26, 2015 – https://doi.org/10.1016/j.jfluchem.2014.10.013
201. Al Sabbagh, C, Tsapis, N, Novell, A., Calleja-Gonzalez, P., Escoffre, JM, Bouakaz A, Chacun, H., Denis, S, Vergnaud, J, Gueutin, C, Fattal, E, Formulation and Pharmacokinetics of thermosensitive stealth® liposomes encapsulating 5-Fluorouracil. Pharmaceutical Research, 32(5):1585-603, 2015 – https://doi.org/10.1007/s11095-014-1559-0
200. Alshaer, W., Hillaireau, H., Vergnaud, J.,Ismail S., Fattal, E., Functionalizing liposomes with anti-CD44 aptamer for selective targeting of cancer cells. Bioconjugate Chemistry, 26 (7), 1307–1313, 2015 – https://doi.org/10.1021/bc5004313
2014
199. Fattal, E., Grabowski, N., Mura, S., Vergnaud, J., Tsapis, N., Hillaireau, H., Lung Toxicity of Biodegradable Nanoparticles. Journal of Biomedical Nanotechnology, 10(10), 2852-2864, 2014 – https://doi.org/10.1166/jbn.2014.1939
198. Fattal, E., Tsapis, N., Nanomedicine technology: current achievements and new trends. Clinical and Translational Imaging, 2(1), 77-87, 2014 – https://doi.org/10.1007/s40336-014-0053-3
197. Belhomme-Henry, C., Phan, G., Huang, N., Bouvier, C., Rebiere, F., Agarande, M., Fattal, E., Texturing formulations for uranium skin decontamination. Pharmaceutical Development and Technology, 19(6), 692-701, 2014 – https://doi.org/10.3109/10837450.2013.823991
196. Diou, O., Fattal, E., Delplace, V., Mackiewicz, N., Nicolas, J., Meriaux, S., Valette, J., Robic, C., Tsapis, N., RGD decoration of PEGylated polyester nanocapsules of perfluorooctyl bromide for tumor imaging: influence of pre or post-functionalization on capsule morphology. European Journal of Pharmaceutics and Biopharmaceutics, 87(1), 170-177, 2014 – https://doi.org/10.1016/j.ejpb.2013.12.003
195. Bol, L., Galas, J.C., Hillaireau, H., Le Potier, I., Nicolas, V., Haghiri-Gosnet, A.M., Fattal, E., Taverna, M., A microdevice for parallelized pulmonary permeability studies. Biomedical Microdevices, 16(2), 277-285, 2014 – https://doi.org/10.1007/s10544-013-9831-3
194. Jafari, S., Diou, O., Mamou, J., Renault, G., Fattal, E., Tsapis, N., Bridal, S.L., High-frequency (20 to 40 MHz) acoustic response of liquid-filled nanocapsules. IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 61(1), 5-15, 2014 – https://doi.org/10.1109/TUFFC.2014.6689771
193. Bruxel, F., Bochot, A., Diel, D., Wild, L., Carvalho, E.L., Cojean, S., Loiseau, P.M., Fattal, E., Teixeira, H.F., Adsorption of antisense oligonucleotides targeting malarial topoisomerase II on cationic nanoemulsions optimized by a full factorial design. Current Topics in Medicinal Chemistry, 14(9), 1161-1171, 2014 – https://doi.org/10.2174/1568026614666140329230835
192. Mousnier, L., Huang, N., Morvan, E., Fattal, E., Tsapis, N., Influence of polymer end-chemistry on the morphology of perfluorohexane polymeric microcapsules intended as ultrasound contrast agents. International Journal of Pharmaceutics, 471(1-2), 10-17, 2014 – https://doi.org/10.1016/j.ijpharm.2014.05.012
191. Giacalone, G., Hillaireau, H., Capiau, P., Chacun, H., Reynaud, F., Fattal, E., Stabilization and cellular delivery of chitosan-polyphosphate nanoparticles by incorporation of iron. Journal of Controlled Release, 194, 211-219, 2014 – https://doi.org/10.1016/j.jconrel.2014.08.022
2013
190. Ismail, S., Alshaer, W., Ababneh, N., Fattal, E., Aptamers: Promising Molecules for Cancer Stem Cell Targeting. Journal of Molecular and Genetic Medicine, 7(90), 1-10, 2013 – http://dx.doi.org/10.4172/1747-0862.1000090
189. Hamoudi, M.C., Saunier, J., Gueutin, C., Fattal, E., Bochot, A., Beads made of alpha-cyclodextrin and soybean oil: the drying method influences bead properties and drug release. Drug Development and Industrial Pharmacy, 39(9), 1306-1314, 2013 –  https://doi.org/10.3109/03639045.2012.727830
188. Gomez-Gaete, C., Bustos, G.L., Godoy, R.R., Saez, C.K., Novoa, G.P., Fernandez, E.M., Tsapis, N., Fattal, E., Successful factorial design for the optimization of methylprednisolone encapsulation in biodegradable nanoparticles. Drug Development and Industrial Pharmacy, 39(2), 310-320, 2013 – https://doi.org/10.3109/03639045.2012.676049
187. Pham, D.D., Fattal, E., Ghermani, N., Guiblin, N., Tsapis, N., Formulation of pyrazinamide-loaded large porous particles for the pulmonary route: avoiding crystal growth using excipients. International Journal of Pharmaceutics, 454(2), 668-677, 2013 – https://doi.org/10.1016/j.ijpharm.2013.04.016
186. Tobar-Grande, B., Godoy, R., Bustos, P., von Plessing, C., Fattal, E., Tsapis, N., Olave, C., Gomez-Gaete, C., Development of biodegradable methylprednisolone microparticles for treatment of articular pathology using a spray-drying technique. International Journal of Nanomedicine, 82065-2076, 2013 – https://doi.org/10.2147/IJN.S39327
185. Grabowski, N., Hillaireau, H., Vergnaud, J., Santiago, L.A., Kerdine-Romer, S., Pallardy, M., Tsapis, N., Fattal, E., Toxicity of surface-modified PLGA nanoparticles toward lung alveolar epithelial cells. International Journal of Pharmaceutics, 454(2), 686-694, 2013 – https://doi.org/10.1016/j.ijpharm.2013.05.025
184. Arpicco, S., Lerda, C., Dalla Pozza, E., Costanzo, C., Tsapis, N., Stella, B., Donadelli, M., Dando, I., Fattal, E., Cattel, L., Palmieri, M., Hyaluronic acid-coated liposomes for active targeting of gemcitabine. European Journal of Pharmaceutics and Biopharmaceutics, 85(3), 373-380, 2013 – https://doi.org/10.1016/j.ejpb.2013.06.003
183. Phan, G., Semili, N., Bouvier-Capely, C., Landon, G., Mekhloufi, G., Huang, N., Rebiere, F., Agarande, M., Fattal, E., Calixarene cleansing formulation for uranium skin contamination. Health Physics, 105(4), 382-389, 2013 – https://doi.org/10.1097/HP.0b013e318298e8d3
182. Ababneh, N., Alshaer, W., Allozi, O., Mahafzah, A., El-Khateeb, M., Hillaireau, H., Noiray, M., Fattal, E., Ismail, S., In vitro selection of modified RNA aptamers against CD44 cancer stem cell marker. Nucleic Acid Therapeutics, 23(6), 401-407, 2013 – https://doi.org/10.1089/nat.2013.0423
181. Giacalone, G., Bochot, A., Fattal, E., Hillaireau, H., Drug-Induced Nanocarrier Assembly as a Strategy for the Cellular Delivery of Nucleotides and Nucleotide Analogues. Biomacromolecules, 14(3), 737-742, 2013 – https://doi.org/10.1021/bm301832v
180. Dalla Pozza, E., Lerda, C., Costanzo, C., Donadelli, M., Dando, I., Zoratti, E., Scupoli, M.T., Beghelli, S., Scarpa, A., Fattal, E., Arpicco, S., Palmieri, M., Targeting gemcitabine containing liposomes to CD44 expressing pancreatic adenocarcinoma cells causes an increase in the antitumoral activity. Biochimica et Biophysica Acta, 1828(5), 1396-1404, 2013 – https://doi.org/10.1016/j.bbamem.2013.01.020
179. Arpicco, S., De Rosa, G., Fattal, E., Lipid-Based Nanovectors for Targeting of CD44-Overexpressing Tumor Cells. Journal of drug delivery, 2013860780-860780, 2013 – https://doi.org/10.1155/2013/860780
2012
178. Diou, O., Tsapis, N., Giraudeau, C., Valette, J., Gueutin, C., Bourasset, F., Zanna, S., Vauthier, C., Fattal, E., Long-circulating perfluorooctyl bromide nanocapsules for tumor imaging by 19FMRI. Biomaterials, 33(22), 5593-5602, 2012 – https://doi.org/10.1016/j.biomaterials.2012.04.037
177. Xiong, B., Pallandre, A., le Potier, I., Audebert, P., Fattal, E., Tsapis, N., Barratt, G., Taverna, M., Electrophoretic mobility measurement by laser Doppler velocimetry and capillary electrophoresis of micrometric fluorescent polystyrene beads. Analytical Methods, 4(1), 183-189, 2012 – https://doi.org/10.1039/C1AY05598D
176. Reul, R., Tsapis, N., Hillaireau, H., Sancey, L., Mura, S., Recher, M., Nicolas, J., Coll, J.-L., Fattal, E., Near infrared labeling of PLGA for in vivo imaging of nanoparticles. Polymer Chemistry, 3(3), 694-702, 2012 – https://doi.org/10.1039/C2PY00520D
175. Nascimento, T.L., Hillaireau, H., Fattal, E., Nanoscale particles for lung delivery of siRNA. Journal of Drug Delivery Science and Technology, 22(1), 99-108, 2012 – https://doi.org/10.1016/S1773-2247(12)50010-9
174. Menard, N., Tsapis, N., Poirier, C., Arnauld, T., Moine, L., Lefoulon, F., Pean, J.-M., Fattal, E., Drug solubilization and in vitro toxicity evaluation of lipoamino acid surfactants. International Journal of Pharmaceutics, 423(2), 312-320, 2012 – https://doi.org/10.1016/j.ijpharm.2011.11.030
173. Menard, N., Tsapis, N., Poirier, C., Arnauld, T., Moine, L., Gignoux, C., Lefoulon, F., Pean, J.-M., Fattal, E., Novel Surfactants with Diglutamic Acid Polar Head Group: Drug Solubilization and Toxicity Studies. Pharmaceutical Research, 29(7), 1882-1896, 2012 – https://doi.org/10.1007/s11095-012-0714-8
172. Hamoudi, M.C., Bourasset, F., Domergue-Dupont, V., Gueutin, C., Nicolas, V., Fattal, E., Bochot, A., Formulations based on alpha cyclodextrin and soybean oil: an approach to modulate the oral release of lipophilic drugs. Journal of Controlled Release, 161(3), 861-867, 2012 – https://doi.org/10.1016/j.jconrel.2012.05.032
171. Dufay Wojcicki, A., Hillaireau, H., Nascimento, T.L., Arpicco, S., Taverna, M., Ribes, S., Bourge, M., Nicolas, V., Bochot, A., Vauthier, C., Tsapis, N., Fattal, E., Hyaluronic acid-bearing lipoplexes: physico-chemical characterization and in vitro targeting of the CD44 receptor. Journal of Controlled Release, 162(3), 545-552, 2012 – https://doi.org/10.1016/j.jconrel.2012.07.015
170. Diou, O., Tsapis, N., Fattal, E., Targeted nanotheranostics for personalized cancer therapy. Expert Opinion on Drug Delivery, 9(12), 1475-1487, 2012 – https://doi.org/10.1517/17425247.2012.736486
169. Bochot, A., Fattal, E., Liposomes for intravitreal drug delivery: A state of the art. Journal of Controlled Release, 161(2), 628-634, 2012 – https://doi.org/10.1016/j.jconrel.2012.01.019
2011
168. Reynaud, F., Tsapis, N., Deyme, M., Vasconcelos, T.G., Gueutin, C., Guterres, S.S., Pohlmann, A.R., Fattal, E., Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption: Kinetic and equilibrium studies. Soft Matter, 7(16), 7304-7312, 2011 – https://doi.org/1010.1039/C1SM05509G
167. Trichard, L., Chaminade, P., Grossiord, J.L., Le Bas, G., Huang, N., Durand, D., Fattal, E., Bochot, A., Beads made of alpha-cyclodextrin and vegetable oils: oil composition and physicochemical properties influence bead feasibility and properties. Journal of Drug Delivery Science and Technology, 21(2), 189-194, 2011 – https://doi.org/10.1016/S1773-2247(11)50021-8
166. Bruxel, F., Cojean, S., Bochot, A., Teixeira, H., Bories, C., Loiseau, P.M., Fattal, E., Cationic nanoemulsion as a delivery system for oligonucleotides targeting malarial topoisomerase II. International Journal of Pharmaceutics, 416(2), 402-409, 2011 – https://doi.org/10.1016/j.ijpharm.2011.01.048
165. Hamoudi, M., Fattal, E., Gueutin, C., Nicolas, V., Bochot, A., Beads made of cyclodextrin and oil for the oral delivery of lipophilic drugs: in vitro studies in simulated gastro-intestinal fluids. International Journal of Pharmaceutics, 416(2), 507-514, 2011 – https://doi.org/10.1016/j.ijpharm.2011.01.062
164. Cruz, L., Fattal, E., Tasso, L., Freitas, G.C., Carregaro, A.B., Guterres, S.S., Pohlmann, A.R., Tsapis, N., Formulation and in vivo evaluation of sodium alendronate spray-dried microparticles intended for lung delivery. Journal of Controlled Release, 152(3), 370-375, 2011 – https://doi.org/10.1016/j.jconrel.2011.02.030
163. Spagnul, A., Bouvier-Capely, C., Phan, G., Landon, G., Tessier, C., Suhard, D., Rebiere, F., Agarande, M., Fattal, E., Ex vivo decrease in uranium diffusion through intact and excoriated pig ear skin by a calixarene nanoemulsion. European Journal of Pharmaceutics and Biopharmaceutics, 79(2), 258-267, 2011 – https://doi.org/10.1016/j.ejpb.2011.05.004
162. Sandolo, C., Pechine, S., Le Monnier, A., Hoys, S., Janoir, C., Coviello, T., Alhaique, F., Collignon, A., Fattal, E., Tsapis, N., Encapsulation of Cwp84 into pectin beads for oral vaccination against Clostridium difficile. European Journal of Pharmaceutics and Biopharmaceutics, 79(3), 566-573, 2011 – https://doi.org/10.1016/j.ejpb.2011.05.004
161. Menard, N., Tsapis, N., Poirier, C., Arnauld, T., Moine, L., Lefoulon, F., Pean, J.M., Fattal, E., Physicochemical characterization and toxicity evaluation of steroid-based surfactants designed for solubilization of poorly soluble drugs. European Journal of Pharmaceutical Sciences, 44(5), 595-601, 2011 – https://doi.org/10.1016/j.ejps.2011.10.006
160. Mura, S., Hillaireau, H., Nicolas, J., Le Droumaguet, B., Gueutin, C., Zanna, S., Tsapis, N., Fattal, E., Influence of surface charge on the potential toxicity of PLGA nanoparticles towards Calu-3 cells. International Journal of Nanomedicine, 62591-2605, 2011 – https://doi.org/10.2147/IJN.S24552
159. Mura, S., Hillaireau, H., Nicolas, J., Kerdine-Roemer, S., Le Droumaguet, B., Delomenie, C., Nicolas, V., Pallardy, M., Tsapis, N., Fattal, E., Biodegradable Nanoparticles Meet the Bronchial Airway Barrier: How Surface Properties Affect Their Interaction with Mucus and Epithelial Cells. Biomacromolecules, 12(11), 4136-4143, 2011 – https://doi.org/10.1021/bm201226x
2010
158. Khoder, M., Tsapis, N., Fattal, E., Mechanisms of antibiotic resistance and delivery strategies to prevent its emergence. Journal of Drug Delivery Science and Technology, 20(6), 407-418, 2010 – https://doi.org/10.1016/S1773-2247(10)50072-8
157. Urbinati, G., Marsaud, V., Plassat, V., Fattal, E., Lesieur, S., Renoir, J.M., Liposomes loaded with histone deacetylase inhibitors for breast cancer therapy. International Journal of Pharmaceutics, 397(1-2), 184-193, 2010 – https://doi.org/10.1016/j.ijpharm.2010.06.046
156. Urbinati, G., Audisio, D., Marsaud, V., Plassat, V., Arpicco, S., Sola, B., Fattal, E., Renoir, J.M., Therapeutic Potential of New 4-hydroxy-tamoxifen-Loaded pH-gradient Liposomes in a Multiple Myeloma Experimental Model. Pharmaceutical Research, 27(2), 327-339, 2010 – https://doi.org/10.1007/s11095-009-0023-z
155. Spagnul, A., Bouvier-Capely, C., Phan, G., Rebiere, F., Fattal, E., Calixarene-Entrapped Nanoemulsion for Uranium Extraction from Contaminated Solutions. Journal of Pharmaceutical Sciences, 99(3), 1375-1383, 2010 – https://doi.org/10.1002/jps.21932
154. Spagnul, A., Bouvier-Capely, C., Phan, G., Rebiere, F., Fattal, E., A new formulation containing calixarene molecules as an emergency treatment of uranium skin contamination. Health Physics, 99(3), 430-434, 2010 – https://doi.org/10.1097/HP.0b013e3181d1a1b6
153. Spagnul, A., Bouvier-Capely, C., Adam, M., Phan, G., Rebiere, F., Fattal, E., Quick and efficient extraction of uranium from a contaminated solution by a calixarene nanoemulsion. International Journal of Pharmaceutics, 398(1-2), 179-184, 2010 – https://doi.org/10.1016/j.ijpharm.2010.07.016
152. Khoder, M., Tsapis, N., Domergue-Dupont, V., Gueutin, C., Fattal, E., Removal of residual colonic ciprofloxacin in the rat by activated charcoal entrapped within zinc-pectinate beads. European Journal of Pharmaceutical Sciences, 41(2), 281-288, 2010 – https://doi.org/10.1016/j.ejps.2010.06.018
151. Giraudeau, C., Flament, J., Marty, B., Boumezbeur, F., Meriaux, S., Robic, C., Port, M., Tsapis, N., Fattal, E., Giacomini, E., Lethimonnier, F., Le Bihan, D., Valette, J., A New Paradigm for High-Sensitivity F-19 Magnetic Resonance Imaging of Perfluorooctylbromide. Magnetic Resonance in Medicine, 63(4), 1119-1124, 2010 – https://doi.org/10.1002/mrm.22269
150. Fritsch, P., Serandour, A.L., Gremy, O., Phan, G., Tsapis, N., Fattal, E., Benech, H., Deverre, J.R., Poncy, J.L., Structure of a single model to describe plutonium and americium decorporation by dtpa treatments. Health Physics, 99(4), 553-559, 2010 – https://doi.org/10.1097/HP.0b013e3181c1cccd
149. Diaz-Lopez, R., Tsapis, N., Santin, M., Bridal, S.L., Nicolas, V., Jaillard, D., Libong, D., Chaminade, P., Marsaud, V., Vauthier, C., Fattal, E., The performance of PEGylated nanocapsules of perfluorooctyl bromide as an ultrasound contrast agent. Biomaterials, 31(7), 1723-1731, 2010 – https://doi.org/10.1016/j.biomaterials.2009.11.044
148. Diaz-Lopez, R., Tsapis, N., Fattal, E., Liquid Perfluorocarbons as Contrast Agents for Ultrasonography and F-19-MRI. Pharmaceutical Research, 27(1), 1-16, 2010 – https://doi.org/10.1007/s11095-009-0001-5
147. Chenal, M., Mura, S., Marchal, C., Gigmes, D., Charleux, B., Fattal, E., Couvreur, P., Nicolas, J., Facile Synthesis of Innocuous Comb-Shaped Polymethacrylates with PEG Side Chains by Nitroxide-Mediated Radical Polymerization in Hydroalcoholic Solutions. Macromolecules, 43(22), 9291-9303, 2010 – https://doi.org/10.1021/ma101880m
2009
146. Taetz, S., Bochot, A., Surace, C., Arpicco, S., Renoir, J.M., Schaefer, U.F., Marsaud, V., Kerdine-Roemer, S., Lehr, C.M., Fattal, E., Hyaluronic Acid-Modified DOTAP/DOPE Liposomes for the Targeted Delivery of Anti-Telomerase siRNA to CD44-Expressing Lung Cancer Cells. Oligonucleotides, 19(2), 103-115, 2009 – https://doi.org/10.1089/oli.2008.0168
145. Surace, C., Arpicco, S., Dufay-Wojcicki, A., Marsaud, V., Bouclier, C., Clay, D., Cattel, L., Renoir, J.M., Fattal, E., Lipoplexes Targeting the CD44 Hyaluronic Acid Receptor for Efficient Transfection of Breast Cancer Cells. Molecular Pharmaceutics, 6(4), 1062-1073, 2009 – https://doi.org/10.1021/mp800215d
144. Roques, C., Fromes, Y., Fattal, E., Hydrosoluble polymers for muscular gene delivery. European Journal of Pharmaceutics and Biopharmaceutics, 72(2), 378-390, 2009 – https://doi.org/10.1016/j.ejpb.2008.11.006
143. Roques, C., Fattal, E., Fromes, Y., Comparison of toxicity and transfection efficiency of amphiphilic block copolymers and polycationic polymers in striated muscles. Journal of Gene Medicine, 11(3), 240-249, 2009 – https://doi.org/10.1002/jgm.1304
142. Roques, C., Bouchemal, K., Ponchel, G., Fromes, Y., Fattal, E., Parameters affecting organization and transfection efficiency of amphiphilic copolymers/DNA carriers. Journal of Controlled Release, 138(1), 71-77, 2009 – https://doi.org/10.1016/j.jconrel.2009.04.030
141. Pisani, E., Ringard, C., Nicolas, V., Raphael, E., Rosilio, V., Moine, L., Fattal, E., Tsapis, N., Tuning microcapsules surface morphology using blends of homo- and copolymers of PLGA and PLGA-PEG. Soft Matter, 5(16), 3054-3060, 2009 – https://doi.org/10.1039/B902042J
140. Khoder, M., Tsapis, N., Huguet, H., Besnard, M., Gueutin, C., Fattal, E., Removal of ciprofloxacin in simulated digestive media by activated charcoal entrapped within zinc-pectinate beads. International Journal of Pharmaceutics, 379(2), 251-259, 2009 – https://doi.org/10.1016/j.ijpharm.2009.05.035
139. Fritsch, P., Serandour, A.L., Gremy, O., Phan, G., Tsapis, N., Abram, M.C., Renault, D., Fattal, E., Benech, H., Deverre, J.R., Poncy, J.L., Simplified Structure of a New Model to Describe Urinary Excretion of Plutonium after Systemic, Liver or Pulmonary Contamination of Rats Associated with Ca-DTPA Treatments. Radiation Research, 171(6), 674-686, 2009 – https://doi.org/10.1667/RR1530.1
138. Fritsch, P., Serandour, A.L., Gremy, O., Le Gall, B., Phan, G., Tsapis, N., Fattal, E., Benech, H., Deverre, J.R., Blanchin, N., Grappin, L., Blanchardon, E., Breustedt, B., Poncy, J.L., Modelling Pu/Am decorporation by DTPA. Radioprotection, 44(4), 431-446, 2009 – https://doi.org/10.1051/radiopro/2009015
137. Fattal, E., Barratt, G., Nanotechnologies and controlled release systems for the delivery of antisense oligonucleotides and small interfering RNA. British Journal of Pharmacology, 157(2), 179-194, 2009 – https://doi.org/10.1111/j.1476-5381.2009.00148.x
136. Diaz-Lopez, R., Tsapis, N., Libong, D., Chaminade, P., Connan, C., Chehimi, M.M., Berti, R., Taulier, N., Urbach, W., Nicolas, V., Fattal, E., Phospholipid decoration of microcapsules containing perfluorooctyl bromide used as ultrasound contrast agents. Biomaterials, 30(8), 1462-1472, 2009 – https://doi.org/10.1016/j.biomaterials.2008.11.032
135. Camelo, S., Lajavardi, L., Bochot, A., Goldenberg, B., Naud, M.C., Brunel, N., Lescure, B., Klein, C., Fattal, E., Behar-Cohen, F., de Kozak, Y., Protective Effect of Intravitreal Injection of Vasoactive Intestinal Peptide-Loaded Liposomes on Experimental Autoimmune Uveoretinitis. Journal of Ocular Pharmacology and Therapeutics, 25(1), 9-21, 2009 – https://doi.org/10.1089/jop.2008.0074
2008
134. Bourgeois, S., Tsapis, N., Honnas, H., Andremont, A., Shakweh, M., Besnard, M., Fattal, E., Colonic delivery of beta-lactamases does not affect amoxicillin pharmacokinetics in rats. Journal of Pharmaceutical Sciences, 97(5), 1853-1863, 2008 – https://doi.org/10.1002/jps.21115
133. Gomez Gaete, C., Tsapis, N., Silva, L., Bourgaux, C., Fattal, E., Morphology, structure and supramolecular organization of hybrid 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine-hyaluronic acid microparticles prepared by spray drying. European Journal of Pharmaceutical Sciences, 34(1), 12-21, 2008 – https://doi.org/10.1016/j.ejps.2008.02.003
132. Fattal, E., Bochot, A., State of the art and perspectives for the delivery of antisense oligonucleotides and siRNA by polymeric nanocarriers. International Journal of Pharmaceutics, 364(2), 237-248, 2008 – https://doi.org/10.1016/j.ijpharm.2008.06.011
131. Trichard, L., Fattal, E., Le Bas, G., Duchene, D., Grossiord, J.L., Bochot, A., Formulation and characterisation of beads prepared from natural cyclodextrins and vegetable, mineral or synthetic oils. International Journal of Pharmaceutics, 354(1-2), 88-94, 2008 – https://doi.org/10.1016/j.ijpharm.2007.10.029
130. Trichard, L., Delgado-Charro, M.B., Guy, R.H., Fattal, E., Bochot, A., Novel beads made of alpha-cyclodextrin and oil for topical delivery of a lipophilic drug. Pharmaceutical Research, 25(2), 435-440, 2008 – https://doi.org/10.1007/s11095-007-9395-0
129. Pisani, E., Tsapis, N., Galaz, B., Santin, M., Berti, R., Taulier, N., Kurtisovski, E., Lucidarme, O., Ourevitch, M., Doan, B.T., Beloeil, J.C., Gillet, B., Urbach, W., Bridal, S.L., Fattal, E., Perfluorooctyl Bromide Polymeric Capsules as Dual Contrast Agents for Ultrasonography and Magnetic Resonance Imaging. Advanced Functional Materials, 18(19), 2963-2971, 2008 – https://doi.org/10.1002/adfm.200800454
128. Pisani, E., Fattal, E., Paris, J., Ringard, C., Rosilio, V., Tsapis, N., Surfactant dependent morphology of polymeric capsules of perfluorooctyl bromide: Influence of polymer adsorption at the dichloromethane-water interface. Journal of Colloid and Interface Science, 326(1), 66-71, 2008 – https://doi.org/10.1016/j.jcis.2008.07.013
127. Martini, E., Fattal, E., de Oliveira, M.C., Teixeira, H., Effect of cationic lipid composition on properties of oligonucleotide/emulsion complexes: Physico-chemical and release studies. International Journal of Pharmaceutics, 352(1-2), 280-286, 2008 – https://doi.org/10.1016/j.ijpharm.2007.10.032
126. Gomez-Gaete, C., Tsapis, N., Silva, L., Bourgaux, C., Besnard, M., Bochot, A., Fattal, E., Supramolecular organization and release properties of phospholipid-hyaluronan microparticles encapsulating dexamethasone. European Journal of Pharmaceutics and Biopharmaceutics, 70(1), 116-126, 2008 – https://doi.org/10.1016/j.ejpb.2008.04.013
125. Gomez-Gaete, C., Fattal, E., Silva, L., Besnard, M., Tsapis, N., Dexamethasone acetate encapsulation into Trojan particles. Journal of Controlled Release, 128(1), 41-49, 2008 – https://doi.org/10.1016/j.jconrel.2008.02.008
124. Diaz-Lopez, R., Libong, D., Tsapis, N., Fattal, E., Chaminade, P., Quantification of pegylated phospholipids decorating polymeric microcapsules of perfluorooctyl bromide by reverse phase HPLC with a charged aerosol detector. Journal of Pharmaceutical and Biomedical Analysis, 48(3), 702-707, 2008 – https://doi.org/10.1016/j.jpba.2008.06.027
123. De Rosa, G., De Stefano, D., Laguardia, V., Arpicco, S., Simeon, V., Carnuccio, R., Fattal, E., Novel cationic liposome formulation for the delivery of an oligonucleotide decoy to NF-kappa B into activated macrophages. European Journal of Pharmaceutics and Biopharmaceutics, 70(1), 7-18, 2008 – https://doi.org/10.1016/j.ejpb.2008.03.012
122. Camelo, S., Lajavardi, L., Bochot, A., Goldenberg, B., Naud, M.C., Fattal, E., Behar-Cohen, F., de Kozak, Y., Drainage of fluorescent liposomes from the vitreous to cervical lymph nodes via conjunctival lymphatics. Ophthalmic Research, 40(3-4), 145-150, 2008 – https://doi.org/10.1159/000119866
121. Breton, P., Larras, V., Roy, D., Sagodira, S., Limal, D., Bonnafous, D., Colin, N., Bru, N., Fattal, E., Couvreur, P., Biocompatible poly(methylidene malonate)-made materials for pharmaceutical and biomedical applications. European Journal of Pharmaceutics and Biopharmaceutics, 68(3), 479-495, 2008 – https://doi.org/10.1016/j.ejpb.2007.08.003
120. Bouclier, C., Moine, L., Hillaireau, H., Marsaud, V., Connault, E., Opolon, P., Couvreur, P., Fattal, E., Renoir, J.M., Physicochemical Characteristics and Preliminary in Vivo Biological Evaluation of Nanocapsules Loaded with siRNA Targeting Estrogen Receptor Alpha. Biomacromolecules, 9(10), 2881-2890, 2008 – https://doi.org/10.1021/bm800664c
2007
119. Gomez-Gaete, C., Tsapis, N., Besnard, M., Bochot, A., Fattal, E., Encapsulation of dexamethasone into biodegradable polymeric nanoparticles. International Journal of Pharmaceutics, 331(2), 153-159, 2007 – https://doi.org/10.1016/j.ijpharm.2006.11.028
118. Trichard, L., Fattal, E., Besnard, M., Bochot, A., alpha-Cyclodextrin/oil beads as a new carrier for improving the oral bioavailability of lipophilic drugs. Journal of Controlled Release, 122(1), 47-53, 2007 – https://doi.org/10.1016/j.jconrel.2007.06.004
117. Serandour, A.L., Tsapis, N., Gervelas, C., Grillon, G., Frechou, M., Deverre, J.R., Benech, H., Fattal, E., Fritsch, P., Poncy, J.L., Decorporation of plutonium by pulmonary administration of Ca-DTPA dry powder: A study in rat after lung contamination with different plutonium forms. Radiation Protection Dosimetry, 127(1-4), 472-476, 2007 – https://doi.org/10.1093/rpd/ncm300
116. Roques, C., Salmon, A., Fiszman, M.Y., Fattal, E., Fromes, Y., Intrapericardial administration of novel DNA formulations based on thermosensitive Poloxamer 407 gel. International Journal of Pharmaceutics, 331(2), 220-223, 2007 – https://doi.org/10.1016/j.ijpharm.2006.11.056
115. Pechine, S., Janoir, C., Boureau, H., Gleizes, A., Tsapis, N., Hoys, S., Fattal, E., Collignon, A., Diminished intestinal colonization by Clostridium difficile and immune response in mice after mucosal immunization with surface proteins of Clostridium difficile. Vaccine, 25(20), 3946-3954, 2007 – https://doi.org/10.1016/j.vaccine.2007.02.055
114. Lajavardi, L., Bochot, A., Camelo, S., Goldenberg, B., Naud, M.C., Behar-Cohen, F., Fattal, E., de Kozak, Y., Downregulation of endotoxin-induced uveitis by intravitreal injection of vasoactive intestinal peptide encapsulated in liposomes. Investigative Ophthalmology & Visual Science, 48(7), 3230-3238, 2007 – https://doi.org/10.1167/iovs.06-1305
113. Gervelas, C., Serandour, A.L., Geiger, S., Grillon, G., Fritsch, P., Taulelle, C., Le Gall, B., Benech, H., Deverre, J.R., Fattal, E., Tsapis, N., Direct lung delivery of a dry powder formulation of DTPA with improved aerosolization properties: Effect on lung and systemic decorporation of plutonium. Journal of Controlled Release, 118(1), 78-86, 2007 – https://doi.org/10.1016/j.jconrel.2006.11.027
112. Dribek, M., Le Potier, I., Rodrigues, A., Pallandre, A., Fattal, E., Taverna, M., Determination of binding constants of vasoactive intestinal peptide to poly(amidoamine) dendrimers designed for drug delivery using ACE. Electrophoresis, 28(13), 2191-2200, 2007 – https://doi.org/10.1002/elps.200600768
111. Camelo, S., Lajavardi, L., Bochot, A., Goldenberg, B., Naud, M.C., Fattal, E., Behar-Cohen, F., de Kozak, Y., Ocular and systemic bio-distribution of rhodamine-conjugated liposomes loaded with VIP injected into the vitreous of Lewis rats. Molecular Vision, 13(256), 2263-2274, 2007 – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268712/
110. Bochot, A., Trichard, L., Le Bas, G., Alphandary, H., Grossiord, J.L., Duchene, D., Fattal, E., alpha-Cyclodextrin/oil beads: An innovative self-assembling system. International Journal of Pharmaceutics, 339(1-2), 121-129, 2007 – https://doi.org/10.1016/j.ijpharm.2007.02.034
2006
109. Fattal, E., Bochot, A., Antisense oligonucleotides, aptamers and SiRNA: promises for the treatment of ocular diseases. Archivos de la Sociedad Espanola de Oftalmologia, 81(1), 3-4, 5-6, 2006 – http://scielo.isciii.es/pdf/aseo/v81n1/en_editorial2.pdf
108. Gomes dos Santos, A.L., Bochot, A., Tsapis, N., Artzner, F., Bejjani, R.A., Thillaye-Goldenberg, B., de Kozak, Y., Fattal, E., Behar-Cohen, F., Oligonucleotide-polyethylenimine complexes targeting retinal cells: structural analysis and application to anti-TGFbeta-2 therapy. Pharmaceutical Research, 23(4), 770-781, 2006 – https://doi.org/10.1007/s11095-006-9748-0
107. Gomes dos Santos, A.L., Bochot, A., Doyle, A., Tsapis, N., Siepmann, J., Siepmann, F., Schmaler, J., Besnard, M., Behar-Cohen, F., Fattal, E., Sustained release of nanosized complexes of polyethylenimine and anti-TGF-beta 2 oligonucleotide improves the outcome of glaucoma surgery. Journal of Controlled Release, 112(3), 369-381, 2006 – https://doi.org/10.1016/j.jconrel.2006.02.010
106. Toub, N., Malvy, C., Fattal, E., Couvreur, P., Innovative nanotechnologies for the delivery of oligonucleotides and siRNA. Biomedicine & Pharmacotherapy, 60(9), 607-620, 2006 – https://doi.org/10.1016/j.biopha.2006.07.093
105. Toub, N., Bertrand, J.R., Tamaddon, A., Elhamess, H., Hillaireau, H., Maksimenko, A., Maccario, J., Malvy, C., Fattal, E., Couvreur, P., Efficacy of siRNA nanocapsules targeted against the EWS-Fli1 oncogene in Ewing sarcoma. Pharmaceutical Research, 23(5), 892-900, 2006 – https://doi.org/10.1007/s11095-006-9901-9
104. Toub, N., Bertrand, J.R., Malvy, C., Fattal, E., Couvreur, P., Antisense oligonucleotide nanocapsules efficiently inhibit EWS-Fli1 expression in a Ewing’s sarcoma model. Oligonucleotides, 16(2), 158-168, 2006 – https://doi.org/10.1089/oli.2006.16.158
103. Shakweh, M., Fattal, E., Design and characterisation of poly(lactide-co-glycolide) small particulate systems for the delivery of immunostimulant CpG oligonucleotide. Journal of Nanoscience and Nanotechnology, 6(9-10), 2811-2820, 2006 – https://doi.org/10.1166/jnn.2006.438
102. Pisani, E., Tsapis, N., Paris, J., Nicolas, V., Cattel, L., Fattal, E., Polymeric nano/microcapsules of liquid perfluorocarbons for ultrasonic imaging: Physical characterization. Langmuir, 22(9), 4397-4402, 2006 – https://doi.org/10.1021/la0601455
101. Phan, G., Le Gall, B., Grillon, G., Rouit, E., Fouillit, M., Benech, H., Fattal, E., Deverre, J.R., Enhanced decorporation of plutonium by DTPA encapsulated in small PEG-coated liposomes. Biochimie, 88(11), 1843-1849, 2006 – https://doi.org/10.1016/j.biochi.2006.06.010
100. Phan, G., Le Gall, B., Deverre, J.R., Fattal, E., Benech, H., Predicting plutonium decorporation efficacy after intravenous administration of DTPA formulations: Study of pharmacokinetic-pharmacodynamic relationships in rats. Pharmaceutical Research, 23(9), 2030-2035, 2006 – https://doi.org/10.1007/s11095-006-9046-x
99. Maillard, S., Gauduchon, J., Marsaud, V., Gouilleux, F., Connault, E., Opolon, P., Fattal, E., Sola, B., Renoir, J.M., Improved antitumoral properties of pure antiestrogen RU 58668-loaded liposomes in multiple myeloma. Journal of Steroid Biochemistry and Molecular Biology, 100(1-3), 67-78, 2006 – https://doi.org/10.1016/j.jsbmb.2006.03.008
98. Fattal, E., Bochot, A., Ocular delivery of nucleic acids: antisense oligonucleotides, aptamers and siRNA. Advanced Drug Delivery Reviews, 58(11), 1203-1223, 2006 – https://doi.org/10.1016/j.addr.2006.07.020
97. Desire, L., Mysiakine, E., Bonnafous, D., Couvreur, P., Sagodira, S., Breton, P., Fattal, E., Sustained delivery of growth factors from methylidene malonate 2.1.2-based polymers. Biomaterials, 27(12), 2609-2620, 2006 – https://doi.org/10.1016/j.biomaterials.2005.11.041
96. Bourgeois, S., Gernet, M., Pradeau, D., Andremont, A., Fattal, E., Evaluation of critical formulation parameters influencing the bioactivity of beta-lactamases entrapped in pectin beads. International Journal of Pharmaceutics, 324(1), 2-9, 2006- https://doi.org/10.1016/j.ijpharm.2006.05.059
2005
95. Bourgeois, S., Harvey, R.D., Fattal, E., Polymer colon drug delivery systems and their applications to peptides, proteins and nucleic acids. American Journal of Drug Delivery, 3(3), 171-204, 2005 – https://doi.org/10.2165/00137696-200503030-00003
94. Harvey, R.D., Bourgeois, S., Pietzonka, L., Desire, L., Fattal, E., Microencapsulation of nanoparticulate complexes of DNA with cationic lipids and polymers in pectin beads for targeted gene delivery. Nanobiotechnology, 1(1), 71-82, 2005 – https://doi.org/10.1385/NBT:1:1:071
93. Gomes Dos Santos, A.L., Bochot, A., Fattal, E., Intraocular delivery of oligonucleotides. Current Pharmaceutical Biotechnology, 6(1), 7-15, 2005 – https://doi.org/10.2174/1389201053167239
92. Ungaro, F., De Rosa, G., Quaglia, F., Fattal, E., La Rotonda, M.I., Controlled release of oligonucleotide/polyethyleneimine complexes from PLGA-based microspheres: potential of spray-drying technique. Journal of Drug Delivery Science and Technology, 15(2), 137-143, 2005 – https://doi.org/10.1016/S1773-2247(05)50018-2
91. Toub, N., Angiari, C., Eboue, D., Fattal, E., Tenu, J.P., Le Doan, T., Couvreur, P., Cellular fate of oligonucleotides when delivered by nanocapsules of poly(isobutylcyanoacrylate). Journal of Controlled Release, 106(1-2), 209-213, 2005 – https://doi.org/10.1016/j.jconrel.2005.03.029
90. Shakweh, M., Besnard, M., Nicolas, V., Fattal, E., Poly (lactide-co-glycolide) particles of different physicochemical properties and their uptake by Peyer’s patches in mice. European Journal of Pharmaceutics and Biopharmaceutics, 61(1-2), 1-13, 2005 – https://doi.org/10.1016/j.ejpb.2005.04.006
89. Phan, G., Herbet, A., Cholet, S., Benech, H., Deverre, J.R., Fattal, E., Pharmacokinetics of DTPA entrapped in conventional and long-circulating liposomes of different size for plutonium decorporation. Journal of Controlled Release, 110(1), 177-188, 2005 – https://doi.org/10.1016/j.jconrel.2005.09.029
88. Maillard, S., Ameller, T., Gauduchon, J., Gougelet, A., Gouilleux, F., Legrand, P., Marsaud, V., Fattal, E., Sola, B., Renoir, J.M., Innovative drug delivery nanosystems improve the anti-tumor activity in vitro and in vivo of anti-estrogens in human breast cancer and multiple myeloma. Journal of Steroid Biochemistry and Molecular Biology, 94(1-3), 111-121, 2005 – https://doi.org/10.1016/j.jsbmb.2004.12.023
87. Maignien, T., Shakweh, M., Calvo, P., Marce, D., Sales, N., Fattal, E., Deslys, J.P., Couvreur, P., Lasmezas, C.I., Role of gut macrophages in mice orally contaminated with scrapie or BSE. International Journal of Pharmaceutics, 298(2), 293-304, 2005 – https://doi.org/10.1016/j.ijpharm.2005.02.042
86. Lavisse, S., Paci, A., Rouffiac, V., Adotevi, C., Opolon, P., Peronneau, P., Bourget, P., Roche, A., Perricaudet, M., Fattal, E., Lassau, N., In vitro echogenicity characterization of poly lactide-coglycolide (PLGA) microparticles and preliminary in vivo ultrasound enhancement study for ultrasound contrast agent application. Investigative Radiology, 40(8), 536-544, 2005 – https://doi.org/10.1097/01.rli.0000170818.03210.ee
85. Bourgeois, S., Laham, A., Besnard, M., Andremont, A., Fattal, E., In vitro and in vivo evaluation of pectin beads for the colon delivery of beta-lactamases. Journal of Drug Targeting, 13(5), 277-284, 2005 – https://doi.org/10.1080/10611860500206583
84. Boulmedarat, L., Piel, G., Bochot, A., Lesieur, S., Delattre, L., Fattal, E., Cyclodextrin-mediated drug release from liposomes dispersed within a bioadhesive gel. Pharmaceutical Research, 22(6), 962-971, 2005 – https://doi.org/10.1007/s11095-005-4591-2
83. Boulmedarat, L., Bochot, A., Lesieur, S., Fattal, E., Evaluation of buccal methyl-beta-cyclodextrin toxicity on human oral epithelial cell culture model. Journal of Pharmaceutical Sciences, 94(6), 1300-1309, 2005 – https://doi.org/10.1002/jps.20350
2004
82. Shakweh, M., Ponchel, G., Fattal, E., Particle uptake by Peyer’s patches: a pathway for drug and vaccine delivery. Expert Opinion on Drug Delivery, 1(1), 141-163, 2004 – https://doi.org/10.1517/17425247.1.1.141
81. Phan, G., Ramounet-Le Gall, B., Manceau, J., Fanet, M., Benech, H., Fritsch, P., Fattal, E., Deverre, J.R., Targeting of diethylene triamine pentaacetic acid encapsulated in liposomes to rat liver: an effective strategy to prevent bone deposition and increase urine elimination of plutonium in rats. International Journal of Radiation Biology, 80(6), 413-422, 2004 – https://doi.org/10.1080/09553000410001702300
80. Fattal, E., De Rosa, G., Bochot, A., Gel and solid matrix systems for the controlled delivery of drug carrier-associated nucleic acids. International Journal of Pharmaceutics, 277(1-2), 25-30, 2004 – https://doi.org/10.1016/j.ijpharm.2003.01.002
79. Fattal, E., Couvreur, P., Dubernet, C., “Smart” delivery of antisense oligonucleotides by anionic pH-sensitive liposomes. Advanced Drug Delivery Reviews, 56(7), 931-946, 2004- https://doi.org/10.1016/j.addr.2003.10.037
2003
78. Quaglia, F., De Rosa, G., Granata, E., Ungaro, F., Fattal, E., Immacolata La Rotonda, M., Feeding liquid, non-ionic surfactant and cyclodextrin affect the properties of insulin-loaded poly(lactide-co-glycolide) microspheres prepared by spray-drying. Journal of Controlled Release, 86(2-3), 267-278, 2003- https://doi.org/10.1016/S0168-3659(02)00414-5
77. Maksimenko, A., Lambert, G., Bertrand, J.R., Fattal, E., Couvreur, P., Malvy, C., Therapeutic potentialities of EWS-Fli-1 mRNA-targeted vectorized antisense oligonucleotides. Annals of the New York Academy of Sciences, 100272-77, 2003 –https://doi.org/10.1196/annals.1281.017
76. Vauthier, C., Dubernet, C., Fattal, E., Pinto-Alphandary, H., Couvreur, P., Poly(alkylcyanoacrylates) as biodegradable materials for biomedical applications. Advanced Drug Delivery Reviews, 55(4), 519-548, 2003 – https://doi.org/10.1016/S0169-409X(03)00041-3
75. Maksimenko, A., Malvy, C., Lambert, G., Bertrand, J.R., Fattal, E., Maccario, J., Couvreur, P., Oligonucleotides targeted against a junction oncogene are made efficient by nanotechnologies. Pharmaceutical Research, 20(10), 1565-1567, 2003 – https://doi.org/10.1023/A:1026122914852
74. De Rosa, G., Quaglia, F., Bochot, A., Ungaro, F., Fattal, E., Long-term release and improved intracellular penetration of oligonucleotide-polyethylenimine complexes entrapped in biodegradable microspheres. Biomacromolecules, 4(3), 529-536, 2003 – https://doi.org/10.1021/bm025684c
73. De Rosa, G., Bochot, A., Quaglia, F., Besnard, M., Fattal, E., A new delivery system for antisense therapy: PLGA microspheres encapsulating oligonucleotide/polyethyleneimine solid complexes. International Journal of Pharmaceutics, 254(1), 89-93, 2003 – https://doi.org/10.1016/S0378-5173(02)00689-0
72. Boulmedarat, L., Grossiord, J.L., Fattal, E., Bochot, A., Influence of methyl-beta-cyclodextrin and liposomes on rheological properties of Carbopol (R) 974P NF gels. International Journal of Pharmaceutics, 254(1), 59-64, 2003 – https://doi.org/10.1016/S0378-5173(02)00683-X
2002
71. De Rosa, G., Quaglia, F., La Rotonda, M., Besnard, M., Fattal, E., Biodegradable microparticles for the controlled delivery of oligonucleotides. International Journal of Pharmaceutics, 242(1-2), 225-228, 2002 – https://doi.org/10.1016/S0378-5173(02)00162-X
70. Fattal, E., Pecquet, S., Couvreur, P., Andremont, A., Biodegradable microparticles for the mucosal delivery of antibacterial and dietary antigens. International Journal of Pharmaceutics, 242(1-2), 15-24, 2002 – https://doi.org/10.1016/S0378-5173(02)00181-3
69. De Rosa, G., Quaglia, F., La Rotonda, M.I., Appel, M., Alphandary, H., Fattal, E., Poly(lactide-co-glycolide) microspheres for the controlled release of oligonucleotide/polyethylenimine complexes. Journal of Pharmaceutical Sciences, 91(3), 790-799, 2002 – https://doi.org/10.1002/jps.10063
68. Couvreur, P., Barratt, G., Fattal, E., Legrand, P., Vauthier, C., Nanocapsule technology: A review. Critical Reviews in Therapeutic Drug Carrier Systems, 19(2), 99-134, 2002 – https://doi.org/10.1615/CritRevTherDrugCarrierSyst.v19.i2.10
67. Bochot, A., Fattal, E., Boutet, V., Deverre, J.R., Jeanny, J.C., Chacun, H., Couvreur, P., Intravitreal delivery of oligonucleotides by sterically stabilized liposomes. Investigative Ophthalmology & Visual Science, 43(1), 253-259, 2002 – http://iovs.arvojournals.org/article.aspx?articleid=2122914
2001
66. Nicoli, S., Santi, P., Couvreur, P., Couarraze, G., Colombo, P., Fattal, E., Design of triptorelin loaded nanospheres for transdermal iontophoretic administration. International Journal of Pharmaceutics, 214(1-2), 31-35, 2001 – https://doi.org/10.1016/S0378-5173(00)00632-3
65. Le Visage, C., Quaglia, F., Dreux, M., Ounnar, S., Breton, P., Bru, N., Couvreur, P., Fattal, E., Novel microparticulate system made of poly(methylidene malonate 2.1.2). Biomaterials, 22(16), 2229-2238, 2001- https://doi.org/10.1016/S0142-9612(00)00411-7
64. Le Visage, C., Couvreur, P., Passirani, C., Breton, P., Bru, N., Fattal, E., Influence of a non-ionic poloxamer surfactant, Pluronic F68, on protein release from poly(methylidene malonate 2.1.2) microparticles in simulated gastric and intestinal media. STP Pharma Sciences, 11(5), 377-383, 2001.
63. Le Visage, C., Couvreur, P., Mysiakine, E., Breton, P., Bru, N., Fattal, E., In vitro and in vivo evaluation of poly(methylidene malonate 2.1.2) microparticles behavior for oral administration. Journal of Drug Targeting, 9(2), 141-153, 2001 – https://doi.org/10.3109/10611860108997924
62. Le Potier, I., Taverna, M., Fattal, E., Benzaki, J., Chevalier, M., Ferrier, D., Performance evaluation of capillary surface treatments for peptide mapping by capillary zone electrophoresis. Chromatographia, 53(9-10), 563-570, 2001 – https://doi.org/10.1007/BF02491624
61. Lambert, G., Fattal, E., Pinto-Alphandary, H., Gulik, A., Couvreur, P., Polyisobutylcyanoacrylate nanocapsules containing an aqueous core for the delivery of oligonucleotides. International Journal of Pharmaceutics, 214(1-2), 13-16, 2001 – https://doi.org/10.1016/S0378-5173(00)00624-4
60. Lambert, G., Fattal, E., Couvreur, P., Nanoparticulate systems for the delivery of antisense oligonucleotides. Advanced Drug Delivery Reviews, 47(1), 99-112, 2001 – https://doi.org/10.1016/S0169-409X(00)00116-2
59. Fattal, E., Dubernet, C., Couvreur, P., Liposome-based formulations for the delivery of oligonucleotides. STP Pharma Science, 11(1), 31-44, 2001.
58. De Oliveira, M.C., Dubernet, C., Paternostre, M., Fattal, E., Couvreur, P., Ollivon, M., pH-sensitive liposomes as a carrier for oligonucleotides (ODN): development of a new methodology to follow physicochemical changes along with pH of native and ODN loaded liposomes. STP Pharma Science, 11(1), 103-107, 2001.
57. Calvo, P., Gouritin, B., Chacun, H., Desmaele, D., D’Angelo, J., Noel, J.P., Georgin, D., Fattal, E., Andreux, J.P., Couvreur, P., Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery. Pharmaceutical Research, 18(8), 1157-1166, 2001 – https://doi.org/10.1023/A:1010931127745
2000
56. Trolle, S., Chachaty, E., Kassis-Chikhani, N., Wang, C., Fattal, E., Couvreur, P., Diamond, B., Alonso, J., Andremont, A., Intranasal immunization with protein-linked phosphorylcholine protects mice against a lethal intranasal challenge with streptococcus pneumoniae. Vaccine, 18(26), 2991-2998, 2000 – https://doi.org/10.1016/S0264-410X(00)00089-X
55. Pecquet, S., Leo, E., Fritsche, R., Pfeifer, A., Couvreur, P., Fattal, E., Oral tolerance elicited in mice by beta-lactoglobulin entrapped in biodegradable microspheres. Vaccine, 18(13), 1196-1202, 2000 – https://doi.org/10.1016/S0264-410X(99)00384-9
54. Neveux, N., De Bandt, J.P., Fattal, E., Hannoun, L., Poupon, R., Chaumeil, J.C., Delattre, J., Cynober, L.A., Cold preservation injury in rat liver: effect of liposomally-entrapped adenosine triphosphate. Journal of Hepatology, 33(1), 68-75, 2000 – https://doi.org/10.1016/S0168-8278(00)80161-0
53. Lambert, G., Fattal, E., Pinto-Alphandary, H., Gulik, A., Couvreur, P., Polyisobutylcyanoacrylate nanocapsules containing an aqueous core as a novel colloidal carrier for the delivery of oligonucleotides. Pharmaceutical Research, 17(6), 707-714, 2000 – https://doi.org/10.1023/A:1007582332491
52. Lambert, G., Bertrand, J.R., Fattal, E., Subra, F., Pinto-Alphandary, H., Malvy, C., Auclair, C., Couvreur, P., EWS Fli-1 antisense nanocapsules inhibits Ewing sarcoma-related tumor in mice. Biochemical and Biophysical Research Communications, 279(2), 401-406, 2000 – https://doi.org/10.1006/bbrc.2000.3963
51. De Oliveira, M.C., Boutet, V., Fattal, E., Boquet, D., Grognet, J.M., Couvreur, P., Deverre, J.R., Improvement of in vivo stability of phosphodiester oligonucleotide using anionic liposomes in mice. Life Sciences, 67(13), 1625-1637, 2000  – https://doi.org/10.1016/S0024-3205(00)00745-1
50. Bochot, A., Couvreur, P., Fattal, E., Intravitreal administration of antisense oligonucleotides: Potential of liposomal delivery. Progress in Retinal and Eye Research, 19(2), 131-147, 2000 – https://doi.org/10.1016/S1350-9462(99)00014-2
1999
49. Trolle, S., Caudron, E., Leo, E., Couvreur, P., Andremont, A., Fattal, E., In vivo fate and immune pulmonary response after nasal administration of microspheres loaded with phosphorylcholine-thyroglobulin. International Journal of Pharmaceutics, 183(1), 73-79, 1999 – https://doi.org/10.1016/S0378-5173(99)00047-2
48. Rojas, J., Pinto-Alphandary, H., Leo, E., Pecquet, S., Couvreur, P., Gulik, A., Fattal, E., A polysorbate-based non-ionic surfactant can modulate loading and release of beta-lactoglobulin entrapped in multiphase poly(DL-lactide-co-glycolide) microspheres. Pharmaceutical Research, 16(2), 255-260, 1999 – https://doi.org/10.1023/A:1018880409254
47. Rojas, J., Pinto-Alphandary, H., Leo, E., Pecquet, S., Couvreur, P., Fattal, E., Optimization of the encapsulation and release of beta-lactoglobulin entrapped poly(DL-lactide-co-glycolide) microspheres. International Journal of Pharmaceutics, 183(1), 67-71, 1999 – https://doi.org/10.1016/S0378-5173(99)00046-0
46. Peracchia, M.T., Fattal, E., Desmaele, D., Besnard, M., Noel, J.P., Gomis, J.M., Appel, M., d’Angelo, J., Couvreur, P., Stealth (R) PEGylated polycyanoacrylate nanoparticles for intravenous administration and splenic targeting. Journal of Controlled Release, 60(1), 121-128, 1999 – https://doi.org/10.1016/S0168-3659(99)00063-2
45. Fattal, E., Delattre, J., Dubernet, C., Couvreur, P., Liposomes for the delivery of nucleotides and oligonucleotides. STP Pharma Science, 9(5), 383-390, 1999.
44. Aynie, I., Vauthier, C., Chacun, H., Fattal, E., Couvreur, P., Spongelike alginate nanoparticles as a new potential system for the delivery of antisense oligonucleotides. Antisense & Nucleic Acid Drug Development, 9(3), 301-312, 1999 – https://doi.org/10.1089/oli.1.1999.9.301
1998
43. Trolle, S., Andremont, A., Fattal, E., Towards a multipurpose mucosal vaccination using phosphorylcholine as a unique antigen? STP Pharma Sciences, 8(1), 19-30, 1998.
42. Skiba-Lahiani, M., Skiba, M., Nikas, G., Auger, J., Fattal, E., Delattre, J., Courtot, A.M., Interaction between PC12 liposomes encapsulating ATP and human spermatozoa. International Journal of Pharmaceutics, 172(1-2), 147-159, 1998 – https://doi.org/10.1016/S0378-5173(98)00203-8
41. Leo, E., Pecquet, S., Rojas, J., Couvreur, P., Fattal, E., Changing the pH of the external aqueous phase may modulate protein entrapment and delivery from poly(lactide-co-glycolide) microspheres prepared by a w/o/w solvent evaporation method. Journal of Microencapsulation, 15(4), 421-430, 1998 – https://doi.org/10.3109/02652049809006869
40. Lambert, G., Fattal, E., Brehier, A., Feger, J., Couvreur, P., Effect of polyisobutylcyanoacrylate nanoparticles and Lipofectin (R) loaded with oligonucleotides on cell viability and PKC alpha neosynthesis in HepG2 cells. Biochimie, 80(12), 969-976, 1998 – https://doi.org/10.1016/S0300-9084(99)80002-9
39. Fattal, E., Vauthier, C., Aynie, I., Nakada, Y., Lambert, G., Malvy, C., Couvreur, P., Biodegradable polyalkylcyanoacrylate nanoparticles for the delivery of oligonucleotides. Journal of Controlled Release, 53(1-3), 137-143, 1998 – https://doi.org/10.1016/S0168-3659(97)00246-0
38. De Oliveira, M.C., Fattal, E., Couvreur, P., Lesieur, P., Bourgaux, C., Ollivon, M., Dubernet, C., pH-Sensitive liposomes as a carrier for oligonucleotides: a physico-chemical study of the interaction between DOPE and a 15-mer oligonucleotide in quasi-anhydrous samples. Biochimica et Biophysica Acta-Biomembranes, 1372(2), 301-310, 1998 – https://doi.org/10.1016/S0005-2736(98)00067-4
37. Bochot, A., Mashhour, B., Puisieux, F., Couvreur, P., Fattal, E., Comparison of the ocular distribution of a model oligonucleotide after topical instillation in rabbits of conventional and new dosage forms. Journal of Drug Targeting, 6(4), 309-313, 1998 – https://doi.org/10.3109/10611869808996838
36. Bochot, A., Fattal, E., Gulik, A., Couarraze, G., Couvreur, P., Liposomes dispersed within a thermosensitive gel: A new dosage form for ocular delivery of oligonucleotides. Pharmaceutical Research, 15(9), 1364-1369, 1998 – https://doi.org/10.1023/A:1011989202488
35. Bochot, A., Fattal, E., Grossiord, J.L., Puisieux, F., Couvreur, P., Characterization of a new ocular delivery system based on a dispersion of liposomes in a thermosensitive gel. International Journal of Pharmaceutics, 162(1-2), 119-127, 1998 – https://doi.org/10.1016/S0378-5173(97)00419-5
34. Allaoui-Attarki, K., Fattal, E., Pecquet, S., Trolle, S., Chachaty, E., Couvreur, P., Andremont, A., Mucosal immunogenicity elicited in mice by oral vaccination with phosphorylcholine encapsulated in poly (D,L-lactide-co-glycolide) microspheres. Vaccine, 16(7), 685-691, 1998 – https://doi.org/10.1016/S0264-410X(97)00261-2
1997
33. Couvreur, P., Fattal, E., Malvy, C., Dubernet, C., pH-sensitive liposomes: an intelligent system for the delivery of antisense oligonucleotides. Journal of Liposome Research, 7(1), 1-18, 1997 – https://doi.org/10.3109/08982109709035478
32. Fernandez-Urrusuno, R., Fattal, E., Feger, J., Couvreur, P., Therond, P., Evaluation of hepatic antioxidant systems after intravenous administration of polymeric nanoparticles. Biomaterials, 18(6), 511-517, 1997 – https://doi.org/10.1016/S0142-9612(96)00178-0
31. Quintilio, W., Sato, R.A., Da Silveira, A.M., Barratt, G., Fattal, E., BuenodaCosta, M.H., Microquantification of proteins with low chromophore content. Biotechnology Techniques, 11(9), 697-700, 1997 – https://doi.org/10.1023/A:1018471713080
30. De Oliveira, M.C., Fattal, E., Ropert, C., Malvy, C., Couvreur, P., Delivery of antisense oligonucleotides by means of pH-sensitive liposomes. Journal of Controlled Release, 48(2-3), 179-184, 1997 – https://doi.org/10.1016/S0168-3659(97)00042-4
29. Couvreur, P., BlancoPrieto, M.J., Puisieux, F., Roques, B., Fattal, E., Multiple emulsion technology for the design of microspheres containing peptides and oligopeptides. Advanced Drug Delivery Reviews, 28(1), 85-96, 1997 – https://doi.org/10.1016/S0169-409X(97)00052-5
28. Blanco-Prieto, M.J., Fattal, E., Gulik, A., Dedieu, J.C., Roques, B.P., Couvreur, P., Characterization and morphological analysis of a cholecystokinin derivative peptide-loaded poly(lactide-co-glycolide) microspheres prepared by a water-in-oil-in-water emulsion solvent evaporation method. Journal of Controlled Release, 43(1), 81-87, 1997 – https://doi.org/10.1016/S0168-3659(96)01474-5
27. Allaoui-Attarki, K., Pecquet, S., Fattal, E., Trolle, S., Chachaty, E., Couvreur, P., Andremont, A., Protective immunity against Salmonella typhimurium elicited in mice by oral vaccination with phosphorylcholine encapsulated in poly(DL-lactide-co-glycolide) microspheres. Infection and Immunity, 65(3), 853-857, 1997 – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC175059/
1996
26. Brazeau, G.A., Sciame, M., al-Suwayeh, S.A., Fattal, E., Evaluation of PLGA microsphere size effect on myotoxicity using the isolated rodent skeletal muscle model. Pharmaceutical Development and Technology, 1(3), 279-283, 1996 – https://doi.org/10.3109/10837459609022596
25. Ramaldes, G.A., Fattal, E., Puisieux, F., Ollivon, M., Solubilization kinetics of phospholipid vesicles by sodium taurocholate. Colloids and Surfaces B-Biointerfaces, 6(6), 363-371, 1996 – https://doi.org/10.1016/0927-7765(96)01278-7
24. Ramaldes, G.A., Deverre, J.R., Grognet, J.M., Puisieux, F., Fattal, E., Use of an enzyme immunoassay for the evaluation of entrapment efficiency and in vitro stability in intestinal fluids of liposomal bovine serum albumin. International Journal of Pharmaceutics, 143(1), 1-11, 1996 – https://doi.org/10.1016/S0378-5173(96)04710-2
23. Nakada, Y., Fattal, E., Foulquier, M., Couvreur, P., Pharmacokinetics and biodistribution of oligonucleotide adsorbed onto poly(isobutylcyanoacrylate) nanoparticles after intravenous administration in mice. Pharmaceutical Research, 13(1), 38-43, 1996 – https://doi.org/10.1023/A:1016017014573
22. Fernandez-Urrusuno, R., Fattal, E., Rodrigues, J.M., Feger, J., Bedossa, P., Couvreur, P., Effect of polymeric nanoparticle administration on the clearance activity of the mononuclear phagocyte system in mice. Journal of Biomedical Materials Research, 31(3), 401-408, 1996 – https://doi.org/10.1002/(SICI)1097-4636(199607)31:3<401::AID-JBM15>3.0.CO;2-L
21. Blanco-Prieto, M.J., Leo, E., Delie, F., Gulik, A., Couvreur, P., Fattal, E., Study of the influence of several stabilizing agents on the entrapment and in vitro release of pBC 264 from poly(lactide-co-glycolide) microspheres prepared by a W/O/W solvent evaporation method. Pharmaceutical Research, 13(7), 1127-1129, 1996 – https://doi.org/10.1023/A:1016087530812
20. Blanco-Prieto, M.J., Durieux, C., Dauge, V., Fattal, E., Couvreur, P., Roques, B.P., Slow delivery of the selective cholecystokinin agonist pBC 264 into the rat nucleus accumbens using microspheres. Journal of Neurochemistry, 67(6), 2417-2424, 1996 – https://doi.org/10.1046/j.1471-4159.1996.67062417.x
1995
19. Aynie, I., Vauthier, C., Foulquier, M., Malvy, C., Fattal, E., Couvreur, P., Development of a quantitative polyacrylamide gel electrophoresis analysis using a multichannel radioactivity counter for the evaluation of oligonucleotide-bound drug carrier. Analytical Biochemistry, 240(2), 202-209, 1996 – https://doi.org/10.1006/abio.1996.0350
18. Fernandez-Urrusuno, R., Fattal, E., Porquet, D., Feger, J., Couvreur, P., Evaluation of liver toxicological effects induced by polyalkylcyanoacrylate nanoparticles. Toxicology and Applied Pharmacology, 130(2), 272-279, 1995 – https://doi.org/10.1006/taap.1995.1032
17. Fernandez-Urrusuno, R., Fattal, E., Porquet, D., Feger, J., Couvreur, P., Influence of surface properties on the inflammatory response to polymeric nanoparticles. Pharmaceutical Research, 12(9), 1385-1387, 1995 – https://doi.org/10.1023/A:1016246312350
16. Skiba-Lahiani, M., Auger, J., Terribile, J., Fattal, E., Delattre, J., Puisieux, F., Jouannet, P., Stimulation of movement and acrosome reaction of human spermatozoa by PC12 liposomes encapsulating ATP. International Journal of Andrology, 18(6), 287-294, 1995 – https://doi.org/10.1111/j.1365-2605.1995.tb00564.x
1994
15. Puisieux, F., Fattal, E., Lahiani, M., Auger, J., Jouannet, P., Couvreur, P., Delattre, J., Liposomes, an interesting tool to deliver a bioenergetic substrate (ATP). in vitro and in vivo studies. Journal of Drug Targeting, 2(5), 443-448, 1994 – https://doi.org/10.3109/10611869408996820
14. Fattal, E., Nir, S., Parente, R.A., Szoka, F.C., Jr., Pore-forming peptides induce rapid phospholipid flip-flop in membranes. Biochemistry, 33(21), 6721-6731, 1994 – https://doi.org/10.1021/bi00187a044
13. Blanco-Prieto, M.J., Delie, F., Fattal, E., Tartar, A., Puisieux, F., Gulik, A., Couvreur, P., Characterization of V3 BRU peptide-loaded small PLGA microspheres prepared by a (W(1)/O)W(2) emulsion solvent evaporation method. International Journal of Pharmaceutics, 111(2), 137-145, 1994 – https://doi.org/10.1016/0378-5173(94)00104-9
1993
12. Maaßen, S., Fattal, E., Muller, R.H., Couvreur, P., Cell cultures for the assessment of toxicity and uptake of polymeric particulate drug carriers. STP Pharma Science, 3(1), 11-22, 1993.
11. Puisieux, F., Fattal, E., Couvreur, P., Rossignol, P., Delattre, J., Liposomes their fate in-vivo and their possible therapeutic use (iv route) – efficiency of liposome-entrapped ATP in cerebral-ischemia. Phosphorus Sulfur and Silicon and the Related Elements, 77(1-4), 661-664, 1993 – https://doi.org/10.1080/10426509308045631
1992
10. Couvreur, P., Fattal, E., Alphandary, H.P., F., Andremont, A., Intracelllular targeting of antibiotics by means of biodegradable nanoparticles. Journal of Controlled Release, 19F259-268, 1992 – https://doi.org/10.1016/0168-3659(92)90081-2
1991
9. Fattal, E., Rojas, J., Roblot-Treupel, L., Andremont, A., Couvreur, P., Ampicillin-loaded liposomes and nanoparticles: comparison of drug loading, drug release and in vitro antimicrobial activity. Journal of Microencapsulation, 8(1), 29-36, 1991 – https://doi.org/10.3109/02652049109021855
8. Fattal, E., Rojas, J., Youssef, M., Couvreur, P., Andremont, A., Liposome-entrapped ampicillin in the treatment of experimental murine listeriosis and salmonellosis. Antimicrobial Agents and Chemotherapy, 35(4), 770-772, 1991 – https://doi.org10.1128/AAC.35.4.770
7. Couvreur, P., Fattal, E., Andremont, A., Liposomes and nanoparticles in the treatment of intracellular bacterial infections. Pharmaceutical Research, 8(9), 1079-1086, 1991 – https://doi.org/10.1023/A:1015885814417
1990
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1989
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1988
4. Laham, A., Claperon, N., Durussel, J.J., Fattal, E., Delattre, J., Puisieux, F., Couvreur, P., Rossignol, P., Liposomally entrapped adenosine triphosphate. Improved efficiency against experimental brain ischaemia in the rat. Journal of Chromatography, 440455-458, 1988 – https://doi.org/10.1016/S0021-9673(00)94549-7
3. Youssef, M., Fattal, E., Alonso, M.J., Roblot-Treupel, L., Sauzieres, J., Tancrede, C., Omnes, A., Couvreur, P., Andremont, A., Effectiveness of nanoparticle-bound ampicillin in the treatment of Listeria monocytogenes infection in athymic nude mice. Antimicrobial Agents and Chemotherapy, 32(8), 1204-1207, 1988 – https://doi.org/10.1128/AAC.32.8.1204
2. Laham, A., Claperon, N., Durussel, J.J., Fattal, E., Delattre, J., Puisieux, F., Couvreur, P., Rossignol, P., Intracarotidal administration of liposomally-entrapped ATP: improved efficiency against experimental brain ischemia. Pharmacological Research Communications, 20(8), 699-705, 1988 – https://doi.org/10.1016/S0031-6989(88)80117-6
1987
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